Ndezvipi zvinokonzerwa ne organic acids ne acidified glycerides mu "resistance inorambidzwa uye resistance yakaderera"?
Kubva pakarambidzwa mishonga yekurwisa mabhakitiriya (AGPs) muEurope muna 2006, kushandiswa kwema organic acids mukudya kwemhuka kwave kuri kukosha zvakanyanya muindasitiri yezvikafu. Kubatsira kwavo pamhando yezvikafu uye mashandiro emhuka kwave kuripo kwemakumi emakore, sezvo vari kuramba vachikwezva kutariswa kweindasitiri yezvikafu.
Chii chinonzi organic acids?
"Organic acids" zvinoreva maasidhi ese anonzi carboxylic acids akavakirwa pamapfupa ekabhoni anogona kushandura chimiro chemuviri chebhakitiriya, zvichikonzera kusagadzikana kwemetabolism izvo zvinodzivirira kuwanda kwemasero uye zvinotungamira kurufu.
Maasidhi ese eorganic anoshandiswa mukudya kwemhuka (akadai se formic acid, propionic acid, lactic acid, acetic acid, sorbic acid kana citric acid) ane chimiro che aliphatic uye ndiwo manyuko esimba emasero. Kusiyana neizvi,
benzoic acidyakavakirwa pamaringi anonhuhwirira uye ine hunhu hwakasiyana hwekugadzirisa muviri uye hwekupinza.
Kuwedzera maasidhi eorganic pahuwandu hwakakodzera muchikafu chemhuka kunogona kuwedzera huremu hwemuviri, kuvandudza kuchinja kwechikafu uye kuderedza kupinda kwezvirwere mumatumbu.
1, kuderedza pH uye kugona kwekuchengetedza chikafu pamwe nemhedzisiro inorwisa mabhakitiriya uye inouraya fungus.
2, nekuburitsa ma hydrogen ions mudumbu kuderedza pH, nokudaro zvichiita kuti pepsinogen igadzire pepsin uye ivandudze kugaya kwemapuroteni;
3. Kudziviswa kwebhakitiriya risingashande zvakanaka mudumbu.
4, metabolites dzepakati - dzinoshandiswa sesimba.
Kushanda kwe organic acid mukudzivirira kukura kwehutachiona kunoenderana nehuwandu hwayo hwe pKa, iyo inotsanangura pH ye acid iri pa50% muchimiro chayo chakaparadzaniswa uye chisina kupatsanurwa. Yekupedzisira ndiyo nzira iyo organic acids ine hunhu hwehutachiona. Kana organic acids dziri muchimiro chadzo chisina kupatsanurwa ndipo padzinogona kupfuura nepamadziro emabhakitiriya nefungi uye kuchinja metabolism yadzo ndipo padzinogona kuuraya utachiona. Saka, izvi zvinoreva kuti kushanda kwe organic acids kunoderedza hutachiona kwakanyanya mumamiriro ezvinhu ane acid (senge mudumbu) uye kunoderera pa pH isina kupararira (mudumbu).
Saka, maasidhi eorganic ane pKa yakakwira maasidhi asina simba uye mishonga inorwisa utachiona inoshanda zvakanyanya muchikafu nekuda kwehuwandu hwakawanda hwemafomu asina kupatsanurwa ari muchikafu, izvo zvinogona kudzivirira chikafu kubva kufungi netupukanana.
Glyceride ine acid
Mumakore ekuma1980, musayendisiti wekuAmerica Agre akawana puroteni yemembrane yesero inonzi aquaporin. Kuwanikwa kwenzira dzemvura kunovhura nzvimbo itsva yekutsvagisa. Parizvino, masayendisiti akawana kuti aquaporin inowanikwa zvakanyanya mumhuka, zvirimwa netupukanana.
Kuburikidza nekugadzirwa kwepropionic acid nebutyric acid neglycerol, α-monopropionic acid glycerol ester, α-monobutyric acid glycerol ester, nekuvhara mabhakitiriya nefungus glycerol channel, zvinokanganisa simba ravo uye membrane dynamic balance, zvekuti vanorasikirwa nemasimba, vanovhara simba rekugadzira kuitira kuti vabate bacterial effect yakanaka, uye kuti vasawane mishonga inouraya.
Kukosha kwepKa kwema organic acids ndiko kudzivirira kwavo tupukanana. Kushanda kwema organic acids kunowanzoenderana nedosi, uye kana chinhu chinoshanda chikasvika panzvimbo yacho, ndipo panodiwa simba rakawanda. Izvi zvinoshanda pakuchengetedza chikafu uye pakuchengetedza hutano hwemhuka. Kana paine ma acids akasimba, munyu wema organic acids unogona kubatsira kuderedza kugona kwekudya uye unogona kupa maanion ekugadzira ma organic acids.
Maglycerides ane acid ane chimiro chakasiyana, α-monopropionate uye α-monobutyric glycerides, ane simba guru rekuuraya mabhakitiriya paSalmonella, Escherichia coli nemamwe mabhakitiriya ane gram-negative uye clostridium nekudzivisa nzira yemvura-glycerine yemabhakitiriya, uye simba iri rekuuraya mabhakitiriya harigumiriswe ne pKa value uye PH value; Haringoiti basa chete muura, asiwo iyi short-chain fatty acid glyceride inonyudzwa zvakananga muropa kuburikidza neura, uye inosvika munzvimbo dzakasiyana dzemuviri dzine hutachiona kuburikidza ne portal vein kuti idzivirire uye idzore zviri nani hutachiona hwehutachiona hwemuviri.
Nguva yekutumira: Nyamavhuvhu-22-2024 
2N`Q)59Z1G}VK.png)
