Ndezvipi zvinokonzeresa organic acids uye acidified glycerides mu "kurambidzwa kuramba uye kuderedzwa kuramba"?
Kubva kurambidzwa kweEuropean pamishonga inorwisa mabhakitiriya (AGPs) muna 2006, kushandiswa kwema organic acids mukudya kwemhuka kwakawedzera kukosha muindasitiri yezvekudya. Kukanganisa kwavo kwakanaka pamhando yekudya uye kuita kwemhuka kwave kuripo kwemakumi emakore, sezvo vari kuwedzera kukwezva kutarisisa kweindasitiri yezvekudya.
Chii chinonzi organic acids?
Organic acids" inoreva maasidhi ese anodaidzwa kuti carboxylic acids akavakirwa pamusoro pekabhoni skeleton anogona kushandura chimiro chemuviri webhakitiriya, zvichikonzera kusagadzikana kwemetabolism inodzivirira kuwanda uye kutungamirira kurufu.
Anenge ese ma organic acids anoshandiswa mukudya kwemhuka (senge formic acid, propionic acid, lactic acid, acetic acid, sorbic acid kana citric acid) ine alphatic chimiro uye isimba masosi emasero. Mukupesana ne,
benzoic acidinovakwa pazvindori zvinonhuhwirira uye ine akasiyana metabolic uye absorption zvimiro.
Kuwedzerwa kwema organic acids pachiyero chakakwirira chedosi mukudya kwemhuka kunogona kuwedzera huremu hwemuviri, kunatsiridza shanduko yekudya uye kuderedza kuumbwa kwehutachiona mumatumbu.
1, dzikisa kukosha kwepH uye buffering kugona mune chikafu pamwe neantibacterial uye antifungal mhedzisiro.
2, nekuburitsa hydrogen ions mudumbu kuderedza pH kukosha, nekudaro activate pepsinogen kuumba pepsin uye kunatsiridza mapuroteni digestibility;
3. Kudzivirirwa kwe gram-negative mabhakitiriya mumugwagwa wepamuviri.
4, yepakati metabolites - inoshandiswa sesimba.
Kubudirira kweiyo organic acid mukudzivisa kukura kwemicrobial kunoenderana neiyo pKa kukosha, iyo inotsanangura pH yeasidhi pa50% mune yayo isina kubatanidzwa uye isina kubatanidzwa fomu. Iyo yekupedzisira ndiyo nzira iyo organic acids ine antimicrobial properties. Izvo chete kana organic acids iri mune yavo isina kubatanidzwa fomu iyo inogona kupfuura nemadziro ebhakitiriya uye fungi uye kuchinja metabolism yavo iyo ine antimicrobial kugona. Nokudaro, izvi zvinoreva kuti antimicrobial efficacy ye organic acids yakakwirira pasi pemamiriro ane acidic (semudumbu) uye yakaderedzwa pa neutral pH (muura).
Nokudaro, organic acids ane high pKa values ane acids shoma uye anonyanya kushanda maantimicrobial muzvokudya nekuda kwehuwandu hwehuwandu hwemafomu asina kubatanidzwa aripo muzvokudya, izvo zvinogona kudzivirira kudya kubva kune fungi uye microorganisms.
Acidified glyceride
Mumakore ekuma1980, musayendisiti wekuAmerica Agre akawana puroteni ye cell membrane inonzi aquaporin. Kuwanikwa kwematanho emvura kunovhura nzvimbo itsva yekutsvaga. Parizvino, masayendisiti akawana kuti aquaporins inowanikwa zvakanyanya mumhuka, zvirimwa uye tupukanana.
Kuburikidza nekugadzirwa kwepropionic acid uye butyric acid uye glycerol, α-monopropionic acid glycerol ester, α-monobutyric acid glycerol ester, nekuvhara mabhakitiriya uye fungi glycerol chiteshi, zvinokanganisa simba ravo uye membrane dynamic chiyero, kuitira kuti varasikirwe nemasimba, block simba synthesis uye bhakteria rekushandisa zvinodhaka kuitira kuti vatambe zvinodhaka.
Iko pKa kukosha kwe organic acids ndiyo inhibitory mhedzisiro yavo pamicroorganisms. Chiito che organic acids chinowanzoenderana nedosi, uye iyo yakawanda yeinoshanda inosvika panzvimbo yekuita, iyo yakakwirira chiito chinodiwa. Izvi zvinoshanda zvese pakuchengetedza chikafu uye kune zvinovaka muviri uye hutano mhedzisiro pamhuka. Kana maasidhi akasimba aripo, munyu weorganic acids unogona kubatsira kuderedza kuvharika kwechikafu uye unokwanisa kupa anions yekugadzira organic acids.
Acidified glycerides ine yakasarudzika chimiro, α-monopropionate uye α-monobutyric glycerides, ine zvinoshamisa bactericidal mhedzisiro paSalmonella, Escherichia coli uye mamwe ma gram-negative mabhakitiriya uye clostridium nekuvharira mvura-glycerine chiteshi chebhakitiriya, uye kukosha kwebhakitiriya uku hakugumirwe nePH. Haisi kungoita basa muura, asiwo iyi pfupi-cheni fatty acid glyceride inonyudzwa zvakananga muropa kuburikidza neura, uye inosvika kumativi akasiyana-siyana ane utachiona hwemuviri kuburikidza nechiteshi chevhavha kuitira kudzivirira zviri nani uye kudzora systemic bhakitiriya utachiona.
Nguva yekutumira: Aug-22-2024 
2N`Q)59Z1G}VK.png)
