Maacids emafuta mapfupi, anosanganisira butyrate nemarudzi ayo anobva, akashandiswa sezvinowedzera zvekudya kuti adzore kana kuderedza migumisiro yakaipa inogona kuwanikwa nezvinhu zvinobva mumiti mukudya kwemhuka dzinorarama mumvura, uye ane zvakawanda zvakaratidzwa zvakanaka zvehutano uye hutano mumhuka dzinoyamwisa nemhuka. Tributyrin, inova butyric acid inobva munyama, yakaongororwa sechinowedzera mukudya kwemhuka dzinochengetwa, nemhedzisiro inovimbisa mumarudzi akati wandei. Muhove nemhuka dzinogara mumvura, kuiswa kwetributyrin mukudya kwazvino uno kwave kuripo uye hakuna kudzidzwa zvakanyanya asi mhedzisiro inoratidza kuti inogona kubatsira zvikuru mhuka dzemumvura. Izvi zvakakosha zvikuru kumhuka dzinodya nyama, dzine kudya kunofanirwa kugadziriswa kuti kuderedzwa kwehuwandu hwehupfu hwehove kuti kuwedzere kuchengetedzeka kwenharaunda uye hupfumi hwechikamu ichi. Basa razvino rinoratidza tributyrin uye rinopa mhedzisiro huru yekushandiswa kwayo senzvimbo yekudya yebutyric acid mukudya kwemhuka dzemumvura. Chinangwa chikuru chinopihwa kumhando dzeaquaculture uye kuti tributyrin, sechinowedzera chikafu, inogona sei kubatsira mukuvandudza kudya kwemvura kubva mumiti.
2. Glyceryl butyrate
Asidhi yebutyric ine hwema husingafadzi uye iri nyore kunyungudika, uye zvakaoma kusvika kumashure kweura kuti iite basa mushure mekudyiwa nemhuka, saka haigone kushandiswa zvakananga mukugadzirwa. Glyceryl butyrate chigadzirwa chine mafuta chebutyric acid neglycerin. Asidhi yebutyric neglycerin zvinosungwa ne covalent bonds. Zvakagadzikana kubva pa pH1-7 kusvika 230 ℃. Mushure mekudyiwa nemhuka, glyceryl butyrate haiori mudumbu, asi inoora kuita butyric acid neglycerin muura pasi pesimba repancreatic lipase, ichiburitsa butyric acid zvishoma nezvishoma. Glyceryl butyrate, sechinowedzerwa chekudya, iri nyore kushandisa, yakachengeteka, haina chepfu, uye ine kuravira kwakakosha. Haingogadzirisi dambudziko rekuti butyric acid yakaoma kuwedzera semvura uye inonhuwa zvakaipa, asiwo inovandudza dambudziko rekuti butyric acid yakaoma kusvika muura kana ikashandiswa zvakananga. Inoonekwa seimwe yezvigadzirwa zvakanakisisa zve butyric acid derivatives uye antihistamine.
2.1 Glyceryl Tributyrate neGlyceryl Monobutyrate
Tributyrinine mamorekuru matatu ebutyric acid uye morekuru imwe yeglycerol. Tributyrin inoburitsa butyric acid zvishoma nezvishoma muura kuburikidza nepancreatic lipase, chikamu chayo chinoburitswa pamberi peura, uye chikamu chayo chinogona kusvika kumashure kweura kuti chiite basa; Monobutyric acid glyceride inoumbwa nemorekuru imwe yebutyric acid inosunga panzvimbo yekutanga yeglycerol (Sn-1 site), ine hydrophilic uye lipophilic properties. Inogona kusvika kumagumo ekumashure kweura nemuto wekugaya. Imwe butyric acid inoburitswa nepancreatic lipase, uye imwe inonyudzwa zvakananga nemasero epithelial emudumbu. Inoora kuita butyric acid neglycerol mumasero emudumbu, zvichikurudzira kukura kweintestinal villi. Glyceryl butyrate ine molecular polarity uye nonpolarity, iyo inogona kupinda zvinobudirira mu hydrophilic kana lipophilic cell wall membrane yebhakitiriya huru inokonzera pathogenic, kupinda mumasero ebhakitiriya, kuparadza chimiro chesero, uye kuuraya mabhakitiriya anokuvadza. Monobutyric acid glyceride ine simba guru rekurwisa mabhakitiriya ane gram-positive uye gram-negative, uye ine simba riri nani rekurwisa mabhakitiriya.
2.2 Kushandiswa kweglyceryl butyrate muzvigadzirwa zvemumvura
Glyceryl butyrate, semushonga unobva mubutyric acid, inogona kuburitsa butyric acid zvinobudirira pasi pesimba remudumbu repancreatic lipase, uye haina hwema, yakasimba, yakachengeteka uye haina masara. Ndiyo imwe yenzira dzakanakisisa dzekushandisa mishonga inorwisa mabhakitiriya uye inoshandiswa zvakanyanya mukurima kwemvura. Zhai Qiuling nevamwe vakaratidza kuti kana 100-150 mg/kg tributylglycerol ester yakawedzerwa muchikafu, mwero wekuwedzera uremu, mwero wekukura chaiwo, mabasa ema enzymes akasiyana-siyana ekugaya uye kureba kwe intestinal villi isati yawedzerwa uye mushure mekuwedzera 100 mg/kg tributylglycerol ester kunogona kuwedzerwa zvakanyanya; Tang Qifeng nevamwe vaongorori vakaona kuti kuwedzera 1.5g/kg tributylglycerol ester kuchikafu kunogona kuvandudza zvakanyanya mashandiro ekukura kwePenaeus vannamei, uye kuderedza zvakanyanya huwandu hwe pathogenic vibrio mudumbu; Jiang Yingying nevamwe. vakawana kuti kuwedzera 1g/kg ye tributyl glyceride muchikafu kunogona kuwedzera zvakanyanya mwero wekuwedzera uremu hweAllogynogenetic crucian carp, kuderedza huwandu hwekudya, uye kuwedzera basa re superoxide dismutase (SOD) mu hepatopancreatic; Dzimwe ongororo dzakaratidza kuti kuwedzerwa kwe1000 mg/kgtributyl glycerideKudya kwacho kunogona kuwedzera zvakanyanya basa remudumbu re superoxide dismutase (SOD) reJian carp.
Nguva yekutumira: Ndira-05-2023
