Kwemakumi emakore butyric acid yave ichishandiswa muindasitiri yezvikafu kuti ivandudze hutano hwedumbu uye mashandiro emhuka. Zvizvarwa zvitsva zvakawanda zvakaunzwa kuti zvivandudze mashandiro echigadzirwa uye mashandiro acho kubvira pakaitwa miedzo yekutanga kuma1980.

Kwemakumi emakore butyric acid yave ichishandiswa muindasitiri yezvikafu kuti ivandudze hutano hwedumbu uye mashandiro emhuka. Zvizvarwa zvitsva zvakawanda zvakaunzwa kuti zvivandudze mashandiro echigadzirwa uye mashandiro acho kubvira pakaitwa miedzo yekutanga muma1980..

1. Kugadzirwa kwebutyric acid sechikafu chinowedzera

Ma1980 > Asidhi yeButyric yakashandiswa kuvandudza kukura kwerumen

Munyu webutyrin acid waishandiswa pakuvandudza mashandiro emhuka muma1990

Munyu wakaputirwa wakagadzirwa mumakore ekuma2000: kuwanikwa kwemudumbu kuri nani uye kunhuhwirira kushoma

2010s> Asidhi itsva yebutyric yakagadziriswa uye inoshanda zviri nani inounzwa

Nhasi uno musika unotongwa nebutyric acid yakachengetedzwa zvakanaka. Vagadziri vezvikafu vanoshanda nezvikafu izvi havana matambudziko nezvinetso zvekunhuhwirira uye mhedzisiro yezvikafu izvi pahutano hwematumbu uye mashandiro azvo iri nani. Dambudziko nezvigadzirwa zvemazuva ano zvakaputirwa nderekuti huwandu hushoma hwebutyric acid. Munyu wakaputirwa unowanzova ne25-30% butyric acid, iyo yakaderera zvikuru.

Kuvandudzwa kwazvino muzvikafu zvinowedzerwa kubva mubutyric acid ndiko kugadzirwa kweProPhorce™ SR: glycerol esters yebutyric acid. Aya ma triglycerides ebutyric acid anogona kuwanikwa mumukaka neuchi. Ndiwo manyuko anoshanda zvakanyanya ebutyric acid yakachengetedzwa ine huwandu hwebutyric acid hunosvika 85%. Glycerol ine mukana wekuva nemamorekuru matatu ebutyric acid akabatanidzwa mairi kuburikidza nezvinonzi 'ester bonds'. Kubatana uku kwakasimba kuripo mu triglycerides dzese uye kunogona kutyorwa chete nema enzymes chaiwo (lipase). Mudumbu nemudumbu tributyrin inoramba isina kukuvadzwa uye mudumbu umo pancreatic lipase inowanikwa zviri nyore, butyric acid inoburitswa.

Maitiro ekusimbisa butyric acid aratidza kuti ndiyo nzira inoshanda zvikuru yekugadzira butyric acid isina hwema inoburitswa kwaunoda: mudumbu.

Basa reTributyrin

1.Inogadzirisa manyoka emudumbu emhuka uye inodzivisa mabhakitiriya anokuvadza mudumbu.

2.Inovandudza kupinza uye kushandisa zvinovaka muviri.

3.Zvinogona kuderedza manyoka uye kushushikana kwemhuka diki.

4.Inowedzera mwero wekurarama uye kuwedzera huremu hwemhuka diki zuva nezuva.