Kwemakumi emakore butyric acid yave ichishandiswa muindasitiri yezvikafu kuti ivandudze hutano hwedumbu uye mashandiro emhuka. Zvizvarwa zvitsva zvakawanda zvakaunzwa kuti zvivandudze mashandiro echigadzirwa uye mashandiro acho kubvira pakaitwa miedzo yekutanga kuma1980.

Kwemakumi emakore butyric acid yave ichishandiswa muindasitiri yezvikafu kuti ivandudze hutano hwedumbu uye mashandiro emhuka. Zvizvarwa zvitsva zvakawanda zvakaunzwa kuti zvivandudze mashandiro echigadzirwa uye mashandiro acho kubvira pakaitwa miedzo yekutanga kuma1980.

1 Kugadzirwa kwebutyric acid sechikafu chinowedzera

Ma1980 > Asidhi yeButyric yakashandiswa kuvandudza kukura kwerumen
Munyu webutyrin acid waishandiswa pakuvandudza mashandiro emhuka muma1990
Munyu wakaputirwa wakagadzirwa mumakore ekuma2000: kuwanikwa kwemudumbu kuri nani uye kunhuhwirira kushoma
2010s> Asidhi itsva yebutyric yakagadziriswa uye inoshanda zviri nani inounzwa

Nhasi uno musika unotongwa nebutyric acid yakachengetedzwa zvakanaka. Vagadziri vezvikafu vanoshanda nezvikafu izvi havana matambudziko nezvinetso zvekunhuhwirira uye mhedzisiro yezvikafu izvi pahutano hwematumbu uye mashandiro azvo iri nani. Dambudziko nezvigadzirwa zvemazuva ano zvakaputirwa nderekuti huwandu hushoma hwebutyric acid. Munyu wakaputirwa unowanzova ne25-30% butyric acid, iyo yakaderera zvikuru.

Kuvandudzwa kwazvino muzvikafu zvinowedzerwa kubva mubutyric acid ndiko kugadzirwa kweProPhorce™ SR: glycerol esters yebutyric acid. Aya ma triglycerides ebutyric acid anogona kuwanikwa mumukaka neuchi. Ndiwo manyuko anoshanda zvakanyanya ebutyric acid yakachengetedzwa ine huwandu hwebutyric acid hunosvika 85%. Glycerol ine mukana wekuva nemamorekuru matatu ebutyric acid akabatanidzwa mairi kuburikidza nezvinonzi 'ester bonds'. Kubatana uku kwakasimba kuripo mu triglycerides dzese uye kunogona kutyorwa chete nema enzymes chaiwo (lipase). Mudumbu nemudumbu tributyrin inoramba isina kukuvadzwa uye mudumbu umo pancreatic lipase inowanikwa zviri nyore, butyric acid inoburitswa.

Maitiro ekusimbisa butyric acid aratidza kuti ndiyo nzira inoshanda zvikuru yekugadzira butyric acid isina hwema inoburitswa kwaunoda: mudumbu. Misiyano nemunyu wakaputirwa yakanyorwa pamufananidzo wechipiri.

Pachirongwa cheESPN chechi20 muPrague, ongororo yekuenzanisa yakaitwa pamusoro pemhedzisiro yezvinowedzera zviviri zvakasiyana zvebutyric acid muhuku dzenyama. Kuedzwa kwakaitwa panzvimbo yekutsvagisa yeADAS muUK muna 2014. Vakaenzanisa munyu wesodium wakaputirwa (une 68% coating) neProPhorce™ SR 130 (55% butyric acid). Nhiyo dzechirume dzeCoss308 720 dzakakamurwa kuita mapoka matatu, nematanga gumi nemaviri eshiri makumi maviri paboka rega rega. Kuti vatevedzere mamiriro ekutengeserana zvakanyanya sezvinobvira, tsvina yakawedzerwa mushure mekuongororwa kwezvirwere zveparasitological, bacterial uye viral.

Basa reTributyrin

1. Inogadzirisa manyoka emudumbu emhuka uye inodzivisa mabhakitiriya anokuvadza mudumbu.

2. Inovandudza kupinza nekushandisa zvinovaka muviri.

3. Inogona kuderedza manyoka nekusvuta kwemhuka diki.

4. Inowedzera mwero wekurarama uye kuwedzera huremu hwemhuka diki zuva nezuva.