Potassium formate, mushonga wekutanga wekudya usina mishonga inorwisa mabhakitiriya wakatenderwa neEuropean Union muna 2001 uye wakatenderwa neBazi rezvekurima reChina muna 2005, wave nehurongwa hwekushandisa hwakakura kwemakore anopfuura gumi, uye mapepa akawanda ekutsvagisa munyika nekunze kwenyika akataura nezvemhedzisiro yawo pamatanho akasiyana-siyana ekukura kwenguruve.

Necrotizing enteritis chirwere chehuku chepasi rose chinokonzerwa nemabhakitiriya ane gram-positive (Clostridium perfringens), icho chinowedzera kufa kwehuku uye kuderedza kukura kwehuku nenzira isingatariswe. Zvese izvi zvinokanganisa kugara zvakanaka kwemhuka uye zvinounza kurasikirwa kukuru kwehupfumi mukuburitswa kwehuku. Mukugadzirwa chaiko, mishonga inorwisa mabhakitiriya inowanzowedzerwa kuchikafu kudzivirira kuitika kwe necrotizing enteritis. Zvisinei, kudanwa kwekurambidzwa kwemishonga inorwisa mabhakitiriya muchikafu kuri kuwedzera, uye dzimwe mhinduro dzinodiwa kutsiva simba rekudzivirira remishonga inorwisa mabhakitiriya. Chidzidzo ichi chakawana kuti kuwedzera organic acids kana munyu wayo muchikafu kunogona kudzivirira huwandu hweClostridium perfringens, nokudaro zvichideredza kuitika kwe necrotizing enteritis. Potassium formate inoora kuita formic acid uye potassium formate mudumbu. Nekuda kwe covalent bond property ku tembiricha, imwe formic acid inopinda mudumbu zvachose. Kuedza uku kwakashandisa huku ine necrotizing enteritis semuenzaniso wekutsvagisa kuti iongorore mhedzisiro yepotassium formatepakukura kwayo, microbiota yemudumbu, uye huwandu hwema "short chain fatty acid" ayo.

1. Mhedzisiro yePotassium Diformatepamusoro peKukura Kwemakushe Enyama Dzakabatwa Nechirwere Chekuora.

Mhedzisiro yekuyedza yakaratidza kuti potassium formate haina kukanganisa zvakanyanya kukura kwehuku dzehuku dzine kana dzisina necrotizing enteritis infection, izvo zvinoenderana nemhedzisiro yekutsvagisa yaHernandez et al. (2006). Zvakaonekwa kuti chiyero chimwe chete checalcium formate hachina kukanganisa zvakanyanya kuwedzera kwehuremu uye huwandu hwekudyisa hwehuku dzehuku, asi kana kuwedzerwa kwecalcium formate kwasvika 15 g/kg, zvakaderedza zvakanyanya kukura kwehuku dzehuku (Patten naWaldroup, 1988). Zvisinei, Selle et al. (2004) vakaona kuti kuwedzera 6 g/kg yepotassium formate mukudya kwakawedzera zvakanyanya kuwedzera kwehuremu uye kudya kwehuku dzehuku dzehuku nemazuva 16-35. Pari zvino pane mishumo mishoma yekutsvagisa pamusoro pebasa re organic acids mukudzivirira necrotizing enteritis infection. Kuedza uku kwakawana kuti kuwedzera 4 g/kg potassium formate mukudya kwakadzikisa zvakanyanya huwandu hwekufa kwehuku dzehuku, asi pakanga pasina hukama hwedose-effect pakati pekudzikira kwehuwandu hwekufa nehuwandu hwe potassium formate yakawedzerwa.

2. Mhedzisiro yePotassium Diformatepamusoro pezvinhu zvidiki zviri munyama nenhengo dzemahuku ane chirwere cheNecrotizing Enteritis

Kuwedzerwa kwe45mg/kg yebacitracin zinc muchikafu kwakaderedza kufa kwehuku dzehuku dzine chirwere che necrotizing enteritis, uye panguva imwe chete kwakaderedza huwandu hweClostridium perfringens mujejunum, izvo zvaienderana nemhedzisiro yekutsvagisa kwaKocher et al. (2004). Pakanga pasina mhedzisiro yakakosha yekuwedzera kwepotassium diformate pane huwandu hweClostridium perfringens mujejunum yehuku dzehuku dzine chirwere che necrotizing enteritis kwemazuva gumi nemashanu. Walsh et al. (2004) vakaona kuti kudya kwe acidity yakawanda kune mhedzisiro yakaipa pa organic acids, saka, acidity yakawanda yekudya kweprotein yakawanda inogona kuderedza mhedzisiro yekudzivirira ye potassium formate pa necrotizing enteritis. Kuedza uku kwakawanawo kuti potassium formate yakawedzera huwandu hwe lactobacilli mudumbu remhasuru dzehuku dzehuku dze35d broiler, izvo zvisingaenderane nekuwana kwaKnarreborg et al. (2002) mu vitro kuti potassium formate yakaderedza kukura kwe lactobacilli mudumbu renguruve.

3.Mhedzisiro yepotassium 3-dimethylformate pa pH yenyama uye huwandu hwemafuta muhuku dzenyama dzine chirwere chebroiler chinouraya enteritis.

Zvinotendwa kuti mhedzisiro yema organic acids inorwisa mabhakitiriya inonyanya kuitika muchikamu chepamusoro chekugaya. Mhedzisiro yekuedza uku yakaratidza kuti potassium dicarboxylate yakawedzera huwandu hwe formic acid mu duodenum pamazuva gumi nemashanu uye jejunum pamazuva makumi matatu nemashanu. Mroz (2005) akawana kuti pane zvinhu zvakawanda zvinokanganisa mashandiro ema organic acids, zvakaita se feed pH, buffering/acidity, uye dietary electrolyte balance. Low acidity uye high electrolyte balance values ​​mukudya zvinogona kukurudzira kupatsanurwa kwe potassium formate kuita formic acid ne potassium formate. Nokudaro, mwero wakakodzera we acidity uye electrolyte balance values ​​mukudya kunogona kuwedzera kuvandudzwa kwekukura kwema broilers ne potassium formate uye kudzivirira kwayo pa necrotizing enteritis.

Mhedziso

Mhedzisiro yepotassium formatePamuenzaniso we necrotizing enteritis muhuku dzebroiler, yakaratidza kuti potassium formate inogona kuderedza kudzikira kwekukura kwehuku dzebroiler pasi pemamwe mamiriro ezvinhu nekuwedzera huremu hwemuviri nekuderedza kufa, uye inogona kushandiswa sechikafu chinowedzera kudzora hutachiona hwe necrotizing enteritis muhuku dzebroiler.