Kutsiva zvishoma zvehupfu hwehove nehupfu hwesoya (SBM) senzira yekuchengetedza hupenyu uye yehupfumi kwave kuongororwa mumhando dzakasiyana dzehupfu hwehove dzinotarisirwa kutengeserana, kusanganisira hove dzemvura yakachena dzinonzi rainbow trout (Oncorhynchus mykissZvisinei, soya nezvimwe zvinhu zvinobva mumiti zvine huwandu hwakawanda hwe saponins nezvimwe zvinhu zvinorwisa kudya zvinokonzeresa subacute enteritis yedumbu riri kure mune dzakawanda dzehove idzi. Dambudziko iri rinoratidzwa nekuwedzera kwekupinda kwemudumbu, kuzvimba, uye kusarongeka kwechimiro zvichikonzera kudzikira kwekushanda kwekudya uye kukanganisa kukura kwehove.

Muhove dzemurarabungu, kusanganisira SBM, pamusoro pe20% yekudya kwakaratidzwa kuti kunokonzera soy-enteritis, zvichiisa chiyero chemuviri padanho rinogona kutsiviwa nekudya kwakajairika kwekuchengetwa kwehove. Ongororo yapfuura yakaongorora nzira dzakasiyana-siyana dzekurwisa chirwere ichi, kusanganisira kushandiswa kwe microbiome yemudumbu, kugadziriswa kwezvinhu zvinodzivirira kushaya chikafu, uye zvimwe zvinodzivirira hutachiona uye zvinodzivirira hutachiona. Imwe nzira isina kuongororwa ndeyekuisa trimethylamine oxide (TMAO) mukudya kwekuchengetwa kwehove. TMAO inodzivirira hutachiona hwese, inounganidzwa mumarudzi akasiyana-siyana seprotein uye membrane stabilizer. Pano, tinoedza kugona kweTMAO kusimudzira kugadzikana kwe enterocyte uye kudzvinyirira chiratidzo cheHSP70 chinoputika nekudaro kurwisa soy-induced enteritis uye zvichitungamira mukuwedzera kushanda kwekudya, kuchengetedza uye kukura kwehove dzemurarabungu dzemvura yakachena. Uyezve, tinoongorora kana zvinonyunguduka muhove dzemugungwa, sosi yakawanda yeTMAO, zvinogona kushandiswa senzira inoshanda yekupa ichi chinowedzera, zvichiita kuti chishandiswe pamusika wekutengesa.

Hove dzemuraraungu (Troutlodge Inc.) dzakachengetwa dzine huremu hwepakati hwe40 g uye n=15 patangi rega rega mumatangi ekurapa matatu. Matangi akapihwa imwe yemhando nhanhatu dzekudya dzakagadzirwa nezvinovaka muviri zvinogayiwa zvinopa 40% mapuroteni anogayiwa, 15% mafuta asina kuchena, uye zvinosangana nehuwandu hwakanaka hweamino acid. Kudya kwacho kwaisanganisira kudya kwehove 40 control (% yekudya kwakaoma), SBM 40, SBM 40 + TMAO 3 g kg^-1, SBM 40 + TMAO 10 g kg^-1, SBM 40 + TMAO 30 g kg^-1, uye SBM 40 + 10% zvinonyunguduka muhove. Matangi akapihwa kaviri pazuva kuti agute kwemavhiki gumi nemaviri uye ongororo dzetsvina, dziri pedyo, dzehistological uye dzemamorekuru dzakaitwa.

Mhedzisiro yechidzidzo ichi ichakurukurwa pamwe nekubatsira kwekushandisa TMAO kuti zvikwanisike kushandiswa zvakanyanya kwezvigadzirwa zvesoya zvekuUS muzvipfuyo zvesalmonid.