Senzira yekutanga ye butyric acid,tributyl glycerideibutyric acid supplement yakanaka kwazvo ine hunhu hwakagadzikana hwemuviri nemakemikari, kuchengetedzeka uye migumisiro isina chepfu. Haingogadzirisi dambudziko rekuti butyric acid inonhuwa zvakaipa uye inoputika nyore nyore, asi inogadzirisawo dambudziko rekuti butyric acid yakaoma kuwedzerwa zvakananga mudumbu nemudumbu. Ine mikana yakawanda yekushandiswa mumunda wekudya kwemhuka. Sechikafu chinowedzera,tributyl glycerideinogona kushanda zvakananga pakugaya kwemhuka, kupa simba remudumbu wemhuka, kuvandudza hutano hwemudumbu wemhuka, uye kudzora kukura kwemhuka nemamiriro ehutano hwayo.

1. Kuvandudza mashandiro ekukura

Kuwedzerwa kwetributyl glycerideKudyisa mhuka kwave kushandiswa zvakanyanya mukugadzira mhando dzese dzemhuka. Kuwedzera huwandu hwakakodzera hwe tributyl glyceride pakudya kunogona kuwedzera huwandu hwehuremu hwemhuka dzinoedza zuva nezuva, kuderedza huwandu hwehuremu hwemhuka dzinoedza, uye kuvandudza kukura kwemhuka. Huwandu hwekuwedzera i0.075% ~ 0.250%.

2. Kuvandudza hutano hwemudumbu

Tributyrininogona kuita basa guru muhutano hwematumbu emhuka nekuvandudza chimiro chemudumbu uye maumbirwo aro, kugadzirisa kuenzana kwemaruva mudumbu, kuvandudza hutachiona hwemudumbu uye kugona kweantioxidant. Chidzidzo ichi chakawana kuti kuwedzera TB mukudya kunogona kuwedzera kuratidzwa kweprotein yemudumbu ine tight junction, kukurudzira kukura kwemucosa yemudumbu, kuvandudza kugayiwa kwezvinovaka muviri zvekudya, kuwedzera kugona kweantioxidant, kuderedza huwandu hwebhakitiriya inokuvadza mudumbu uye kuwedzera huwandu hwebhakitiriya inobatsira, kukurudzira kukura kwemudumbu wemhuka, uye kuvandudza hutano hwemudumbu wemhuka.

Kune zvimwe zvidzidzo zvakaratidza kuti kuwedzerwa kweTB mukudya kunogona kuvandudza zvikuru kugayiwa kwemapuroteni asina kuchekwa, mafuta asina kuchekwa nesimba renguruve dzakarumurwa, uye kugayiwa kwezvinovaka muviri zvekudya kwakabatana zvakanyanya nehutano hwematumbu emhuka. Zvinogona kuonekwa kuti TB inokurudzira kunyudzwa nekugayiwa kwezvinovaka muviri mudumbu.

Kuwedzera kwetributyl glycerideinogona kuwedzera zvakanyanya kukwirira kwevillus uye kukosha kweV/C kwemudumbu wenguruve dziri kurumurwa, kuderedza huwandu hweMDA nehydrogen peroxide mujejunum, kuwedzera mashandiro emitochondrial, kuderedza kushushikana kweoxidative munguruve, uye kukurudzira kukura kwedumbu.

Kuwedzera tributyl glyceride ine microcapsulated kunogona kuwedzera zvakanyanya kukwirira kwevillus kwe duodenum ne jejunum, kuwedzera huwandu hwe lactic acid bacteria mu cecum uye kuderedza huwandu hwe Escherichia coli, kugadzirisa chimiro chemukati chehuku dzehuku, uye mhedzisiro ye microcapsulated TB iri nani pane ye liquid TB. Nekuda kwebasa rakakosha re rumen mu ruminants, hapana mishumo mishoma pamusoro pemhedzisiro ye tributyl glyceride pa ruminants.

Sezvo iri simba remudumbu, tributyrin inogona kuvandudza nekugadzirisa chimiro chemudumbu, kugadzirisa kugona kwekugaya chikafu nekupinza mudumbu, kukurudzira kuwanda kwemabhakitiriya anobatsira mudumbu, kugadzirisa chimiro chemaruva emudumbu, kuderedza oxidative stress reaction yemhuka, kukurudzira kukura kwemudumbu, uye kuona hutano hwemuviri.

Chidzidzo chacho chakawana kuti kuwedzerwa kwetributyrinuye oiri ye oregano kana methyl salicylate mukudya kwenguruve dzakarumurwa zvinogona kuwedzera V/C kukosha kweura, kuvandudza chimiro cheura hwenguruve, kuwedzera zvakanyanya kuwanda kweFirmicutes, kuderedza kuwanda kweProteus, Actinobacillus, Escherichia coli, nezvimwewo, kushandura chimiro chemaruva emudumbu uye metabolites, izvo zvinobatsira hutano hweura hwenguruve dzakarumurwa, uye zvinogona kutsiva mishonga inorwisa mabhakitiriya pakushandisa nguruve dzakarumurwa.

Kazhinji,tributyrinine mabasa akasiyana-siyana ehupenyu akadai sekupa simba mumuviri, kuchengetedza hutano hwemudumbu, kudzora chimiro chemaruva emudumbu, kutora chikamu mukuita kwekudzivirira muviri uye metabolic reactions, nezvimwewo. Inogona kukurudzira kukura kwemudumbu wemhuka uye kuvandudza mashandiro ekukura kwemhuka. Glyceryl tributylate inogona kuodzwa nepancreatic lipase mudumbu kuti igadzire butyric acid neglycerol, izvo zvinogona kushandiswa senzvimbo inoshanda yebutyric acid mudumbu remhuka. Haingogadziri dambudziko rekuti butyric acid yakaoma kuwedzera muchikafu nekuda kwekunhuhwirira kwayo uye kusagadzikana kwayo, asiwo inogadzirisa dambudziko rekuti butyric acid yakaoma kupinda mudumbu nedumbu. Inotsiva mishonga inorwisa mabhakitiriya inoshanda zvikuru, yakachengeteka uye yakasvibira.

Zvisinei, tsvakiridzo yazvino pamusoro pekushandiswa kwetributyl glycerideMukudya kwemhuka kushoma, uye tsvakiridzo pamusoro pehuwandu, nguva, chimiro uye musanganiswa weTB nezvimwe zvinovaka muviri haikoshi. Kusimbisa kushandiswa kwetributyl glyceride mukugadzirwa kwemhuka hakungogone kupa nzira itsva dzekuchengetedza hutano hwemhuka nekudzivirira zvirwere chete, asiwo kune kukosha kukuru mukugadzirwa kwemishonga inotsiva mishonga inorwisa mabhakitiriya, ine mikana yakawanda yekushandiswa.